Article
Acute hyperinsulinemia decreases the hepatic secretion of very-low-density lipoprotein apolipoprotein B-100 in NIDDM.
Diabetes - 1 Sept 1995
Cummings M H, Watts G F, Umpleby A M, Hennessy T R, Kelly J M, Jackson N C, Sönksen P H
Abstract excerpt
In a randomized crossover study, we measured the hepatic secretion rate of very-low-density lipoprotein (VLDL) apolipoprotein B-100 (apoB) in seven patients with well-controlled non-insulin-dependent diabetes mellitus (NIDDM) (HbA1 8.4 +/- 0.4% [mean +/- SE]) on two occasions: during a 13-h hyperinsulinemic (plasma insulin concentration 586 +/- 9.7 pmol/l) euglycemic (plasma glucose concentration 5.2 +/- 0.1...
Topics
- Apolipoprotein B-100
- Apolipoproteins B
- Apolipoproteins E
- C-Peptide
- Cross-Over Studies
- Diabetes Mellitus, Type 2
- Female
- Glucose Clamp Technique
- Humans
- Hyperinsulinism
- Infusions, Intravenous