Article
Colonizing populations of Candida albicans are clonal in origin but undergo microevolution through C1 fragment reorganization as demonstrated by DNA fingerprinting and C1 sequencing.
Journal of clinical microbiology - 1 Jun 1995
Lockhart S R, Fritch J J, Meier A S, Schröppel K, Srikantha T, Galask R, Soll D R
Abstract excerpt
The genetic homogeneity of nine commensal and infecting populations of Candida albicans has been assessed by fingerprinting multiple isolates from each population by Southern blot hybridization first with the Ca3 probe and then with the 0.98-kb C1 fragment of the Ca3 probe. The isolates from each...
Topics
- Base Sequence
- Biological Evolution
- Candida albicans
- Candidiasis, Oral
- Candidiasis, Vulvovaginal
- DNA Fingerprinting
- DNA, Fungal
- Female
- Gene Rearrangement
- Genes, Fungal
- Genetic Variation
- Humans
- Molecular Probes
- Molecular Sequence Data