Article
Restriction fragment length polymorphisms at the apoprotein genes AI, CIII and B-100 and in the 5' flanking region of the insulin gene as possible markers of coronary heart disease.
Clinical genetics - 1 Apr 1995
Wick U, Witt E, Engel W
Abstract excerpt
Several sequence variations were examined for being endogenous "risk markers" in the development of CHD. The "markers" in this study included: the PstI-SstI RFLPs in the apo AI-CIII gene cluster, the EcoRI-MspI RFLPs in the apo B100 gene and the SstI RFLP in the 5' flanking region of the insulin...
Topics
- Aged
- Alleles
- Apolipoprotein A-I
- Apolipoprotein B-100
- Apolipoprotein C-III
- Apolipoproteins B
- Apolipoproteins C
- Cholesterol
- Coronary Disease
- Female
- Genetic Markers
- Genotype
- Humans
- Infant, Newborn
- Insulin
- Male
- Polymorphism, Restriction Fragment Length
- Triglycerides