Article
Apolipoprotein E polymorphism, serum lipids, myocardial infarction and severity of angiographically verified coronary artery disease in men and women.
Atherosclerosis - 7 Apr 1995
Lehtinen S, Lehtimäki T, Sisto T, Salenius J P, Nikkilä M, Jokela H, Koivula T, Ebeling F, Ehnholm C
Abstract excerpt
In several populations, the apolipoprotein E (apo E) allele epsilon 4 is associated with high concentration of plasma total and low density lipoprotein (LDL)-cholesterol and coronary artery disease (CAD). We determined the apo E phenotypes of 309 patients with angiographically verified CAD and 38 patients without CAD by isoelectric focusing and Western blotting. In men with CAD, the plasma total and...
Topics
- Age Distribution
- Aged
- Alleles
- Analysis of Variance
- Apolipoproteins E
- Cholesterol
- Cholesterol, HDL
- Cholesterol, LDL
- Coronary Angiography
- Coronary Disease
- Female