Identification of a novel response regulator required for the swarmer-to-stalked-cell transition in Caulobacter crescentus.

Abstract excerpt

The onset of motility late in the Caulobacter crescentus cell cycle depends on a signal transduction pathway mediated by the histidine kinase PleC and response regulator DivK. We now show that pleD, whose function is required for the subsequent loss of motility and stalk formation by the motile swarmer cell, encodes a 454-residue protein with tandem N-terminal response regulator domains D1 and D2 and a novel...

Topics

• Alleles
• Amino Acid Sequence
• Bacterial Proteins
• Base Sequence
• Caulobacter crescentus
• Cell Cycle
• Cell Differentiation
• Cloning, Molecular
• Genes, Bacterial
• Genetic Complementation Test
• Models, Biological