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Article

Cocaine alters myosin isoform expression in the rat soleus.

Journal of applied physiology (Bethesda, Md. : 1985) - 1 Aug 1995

Prevost M C, Nelson A G, Kelly K P, Han D H, Conlee R K

Abstract excerpt

The purpose of this study was to determine whether chronic cocaine administration alters the expression of myosin isoforms in the rat soleus. Forty-five adult Sprague-Dawley rats were divided into three groups: chronic cocaine (n = 15), 12.5 mg/kg cocaine-HCl injected intraperitoneally twice daily for 14 days and one injection of cocaine (12.5 mg/kg ip) on day 15; acute cocaine (n = 15), saline injections twice...

Topics

Animals
Cocaine
Electrophoresis, Polyacrylamide Gel
Isomerism
Muscle, Skeletal
Myofibrils
Myosin Heavy Chains
Myosins
Phenotype
Rats
Rats, Sprague-Dawley
Sympathomimetics

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Source

Identifiers

PMID: 7592211
DOI: 10.1152/jappl.1995.79.2.514

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7592211-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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