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Article

Somatic mutations of von Hippel-Lindau (VHL) tumor-suppressor gene in European kidney cancers.

International journal of cancer - 27 Nov 1995

Bailly M, Bain C, Favrot M C, Ozturk M

Abstract excerpt

Somatic mutations of von Hippel Lindau (VHL) tumor-suppressor gene have been identified in kidney cancers from North America and Japan. We studied VHL gene mutation in 31 kidney tumors from France. Of these tumors, 45% (14/31) displayed mutations, 60% of which occurred at A:T base pairs. The frequency and the spectrum of mutations identified in kidney tumors from Europe were similar to those reported for tumors...

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Identifiers

PMID: 7591282
DOI: 10.1002/ijc.2910630510

Genes

VHL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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Somatic mutations of von Hippel-Lindau (VHL) tumor-suppressor gene in European kidney cancers.PMID 7591282Read ↗

Germline mutations in the Von Hippel-Lindau disease (VHL) gene in families from North America, Europe, and Japan.Semantic proximity Read ↗

Germline and somatic mutations in von Hippel-Lindau disease gene and its significance in the development of kidney cancer.Semantic proximity Read ↗

Unique molecular alteration patterns in von Hippel-Lindau (VHL) gene in a cohort of sporadic renal cell carcinoma patients from Pakistan.Semantic proximity Read ↗

Mutations in the VHL tumor suppressor gene and associated lesions in families with von Hippel-Lindau disease from central Europe.Semantic proximity Read ↗

Identification of somatic mutations in the von Hippel-Lindau (VHL) gene in a patient with renal cell carcinoma.Semantic proximity Read ↗

Germline mutation of Glu70Lys is highly frequent in Korean patients with von Hippel-Lindau (VHL) disease.Semantic proximity Read ↗

Germ-line mutations in the von Hippel-Lindau tumor-suppressor gene are similar to somatic von Hippel-Lindau aberrations in sporadic renal cell carcinoma.Semantic proximity Read ↗

Germline mutations in the von Hippel-Lindau disease (VHL) gene in Japanese VHL. Clinical Research Group for VHL in Japan.Semantic proximity Read ↗

Germ-line mutation analysis in patients with von Hippel-Lindau disease in Japan: an extended study of 77 families.Semantic proximity Read ↗

Identification of the von Hippel-Lindau (VHL) gene. Its role in renal cancer.Semantic proximity Read ↗

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