Article
Creating a Drosophila wing de novo, the role of engrailed, and the compartment border hypothesis.
Development (Cambridge, England) - 1 Oct 1995
Tabata T, Schwartz C, Gustavson E, Ali Z, Kornberg T B
Abstract excerpt
Anterior/posterior compartment borders bisect every Drosophila imaginal disc, and the engrailed gene is essential for their function. We analyzed the role of the engrailed and invected genes in wing discs by eliminating or increasing their activity. Removing engrailed/invected from posterior wing cells created two new compartments: an anterior compartment consisting of mutant cells and a posterior compartment...
Topics
- Animals
- Cloning, Molecular
- Drosophila
- Drosophila Proteins
- Female
- Gene Deletion
- Gene Expression
- Genes, Insect
- Homeodomain Proteins
- Insect Hormones
- Morphogenesis
