Article
[Meniere disease as an autosome dominant hereditary disease].
Laryngo- rhino- otologie - 1 Aug 1995
Arweiler D J, Jahnke K, Grosse-Wilde H
Abstract excerpt
Within one year (1993) we found a positive family history in five out of forty-eight new patients with Menière's disease, corresponding to a frequency of 10.4%. We found between two and seven cases in each of five families. The disease followed a dominant autosomal hereditary pattern over two to four generations. Audiometric and vestibulometric examination confirmed the diagnosis. Clinical emphasis was placed on...
Topics
- Adult
- Audiometry, Pure-Tone
- Chromosome Aberrations
- Chromosome Disorders
- Female
- Gene Frequency
- Genes, Dominant
- HLA-A2 Antigen
- HLA-B Antigens
- HLA-B44 Antigen
- Humans
- Male