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Article

Spatial working memory deficits in the relatives of schizophrenic patients.

Archives of general psychiatry - 1 Oct 1995

Park S, Holzman P S, Goldman-Rakic P S

Abstract excerpt

BACKGROUND: Studies in nonhuman primates provide evidence that intact spatial working memory depends on the integrity of specific areas in the prefrontal cortex. Patients with schizophrenia have been shown to be impaired on spatial working memory tasks. Relatives of schizophrenic patients show a range of cognitive deficits in the absence of clinical symptoms (eg, thought disorder, eye tracking dysfunctions). We...

Topics

Adult
Eye Movements
Family
Female
Form Perception
Humans
Male
Memory Disorders
Phenotype
Prefrontal Cortex
Psychomotor Performance
Reaction Time

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Schizophrenia

Schizophrenic Psychology

Space Perception

Source

Identifiers

PMID: 7575101
DOI: 10.1001/archpsyc.1995.03950220031007

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7575101-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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