Article
The contribution of vitamin D receptor gene alleles to the determination of bone mineral density in normal and osteoporotic women.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Jun 1995
Riggs B L, Nguyen T V, Melton L J, Morrison N A, O'Fallon W M, Kelly P J, Egan K S, Sambrook P N, Muhs J M, Eisman J A
Abstract excerpt
Bone mass and its mineral content are under genetic control. The vitamin D receptor (VDR) gene has been shown to be a major locus for genetic effects on bone mineral density (BMD), and polymorphisms in this gene accounted for a large proportion of genetic variance in BMD in an Australian populati...
Topics
- Aged
- Alleles
- Analysis of Variance
- Base Sequence
- Biomarkers
- Bone Density
- DNA Primers
- Female
- Genotype
- Humans
- Leukocyte Count
- Middle Aged
- Minnesota
- Molecular Sequence Data