Article
[Risk assessment for familial occurrence of breast cancer].
Zentralblatt fur Gynakologie - 1 Jan 1995
Chang-Claude J, Becher H, Hamann U, Schroeder-Kurth T
Abstract excerpt
There is now unequivocal evidence that an estimated 5% of breast cancer cases is inherited in families. Inherited predisposition of cancer in these families is thought to be the result of a mutation in one of several highly penetrant autosomal dominant genes such as BRCA1 or BRCA2. The BRCA1 gene...
Topics
- Adult
- Aged
- BRCA1 Protein
- BRCA2 Protein
- Breast Neoplasms
- Chromosome Aberrations
- Chromosome Disorders
- Chromosomes, Human, Pair 13
- Chromosomes, Human, Pair 17
- Female
- Genetic Counseling
- Genetic Testing
- Humans
- Middle Aged
- Neoplasm Proteins
- Neoplastic Syndromes, Hereditary
- Pedigree
- Phenotype
