Article
Mating patterns in malaria parasite populations of Papua New Guinea.
Science (New York, N.Y.) - 22 Sept 1995
Paul R E, Packer M J, Walmsley M, Lagog M, Ranford-Cartwright L C, Paru R, Day K P
Abstract excerpt
Description of the genetic structure of malaria parasite populations is central to an understanding of the spread of multiple-locus drug and vaccine resistance. The Plasmodium falciparum mating patterns from madang, Papua New Guinea, where intense transmission of malaria occurs, are described here. A high degree of inbreeding occurs in the absence of detectable linkage disequilibrium. This contrasts with other...
Topics
- Alleles
- Animals
- Anopheles
- Antimalarials
- Base Sequence
- Drug Resistance
- Female
- Genes, Protozoan
- Genetic Variation
- Genotype
- Heterozygote
- Humans
