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Article

Recoverin, a photoreceptor-specific calcium-binding protein, is expressed by the tumor of a patient with cancer-associated retinopathy.

26 Sept 1995

Abstract excerpt

Recoverin is a member of the EF-hand family of calcium-binding proteins involved in the transduction of light by vertebrate photoreceptors. Recoverin also was identified as an autoantigen in the degenerative disease of the retina known as cancer-associated retinopathy (CAR), a paraneoplastic syndrome whereby immunological events lead to the degeneration of photoreceptors in some individuals with cancer. In this...

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Identifiers

PMID: 7568096
DOI: 10.1073/pnas.92.20.9176

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Related research

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Research trail→

Click a neighbor to travelStep 1 · 8 closest

Recoverin, a photoreceptor-specific calcium-binding protein, is expressed by the tumor of a patient with cancer-associated retinopathy.PMID 7568096Read ↗

Unique retina cell phenotypes revealed by immunological analysis of recoverin expression in rat retina cells.Semantic proximity Read ↗

Recoverin negative photoreceptor cells.Semantic proximity Read ↗

Comparative proteomic analysis of differentially expressed proteins in primary retinoblastoma tumorsSemantic proximity Read ↗

Structure and membrane-targeting mechanism of retinal Ca2+-binding proteins, recoverin and GCAP-2.Semantic proximity Read ↗

Recoverin binds exclusively to an amphipathic peptide at the N terminus of rhodopsin kinase, inhibiting rhodopsin phosphorylation without affecting catalytic activity of the kinase.Semantic proximity Read ↗

Peripheral expression of rod photoreceptor arrestin induces an epitope-specific, protective response against experimental autoimmune uveoretinitis.Semantic proximity Read ↗

Recoverin is a zinc-binding protein.Semantic proximity Read ↗

Calcium negatively regulates an intramolecular interaction between the N-terminal recoverin homology and EF-hand motif domains and the C-terminal C1 and catalytic domains of diacylglycerol kinase α.Semantic proximity Read ↗

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