Article
Complete detection of mutations in cystic fibrosis patients of Native American origin.
Human genetics - 1 Dec 1994
Mercier B, Raguénès O, Estivill X, Morral N, Kaplan G C, McClure M, Grebe T A, Kessler D, Pignatti P F, Marigo C
Abstract excerpt
An increased incidence of cystic fibrosis (CF) has been reported in some populations of Native Americans of the Southwest such as the Pueblo, which is a genetic isolate. As the most common mutation found in Caucasians (delta F508) was absent and only one chromosome carried the G542X mutation, we...
Topics
- Base Sequence
- Cystic Fibrosis
- Cystic Fibrosis Transmembrane Conductance Regulator
- Humans
- Indians, North American
- Membrane Proteins
- Molecular Sequence Data
- Mutation