Article
Genetic history of cystic fibrosis mutations in Italy. I. Regional distribution.
Annals of human genetics - 1 Sept 1997
Rendine S, Calafell F, Cappello N, Gagliardini R, Caramia G, Rigillo N, Silvetti M, Zanda M, Miano A, Battistini F, Marianelli L, Taccetti G, Diana M C, Romano L, Romano C, Giunta A, Padoan R, Pianaroli A, Raia V, De Ritis G, Battistini A, Grzincich G, Japichino L, Pardo F, Piazza A
Abstract excerpt
Earlier analysis of the Italian population showed patterns of genetic differentiation that were interpreted as being the result of population settlements going back to pre-Roman times. DNA disease mutations may be a powerful tool in further testing this hypothesis since the analysis of diseased i...
Topics
- Cystic Fibrosis
- Factor Analysis, Statistical
- Gene Frequency
- Genetics, Population
- Humans
- Italy
- Mutation
- Phylogeny