Maternal serum pregnancy‐associated plasma protein a and fetal nuchal translucency thickness for the prediction of fetal trisomies in early pregnancy

Abstract excerpt

OBJECTIVE: To determine if the risk for fetal trisomies during the first trimester of pregnancy can be derived by combining data from maternal serum pregnancy-associated plasma protein A (PAPP-A) and fetal nuchal translucency thickness. METHODS: Pregnancy-associated plasma protein A was measured in samples from 87 singleton pregnancies with fetal chromosomal abnormalities (45 trisomy 21, 19 trisomy 18, eight...