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Article

Neutralization-resistant variants of infectious hematopoietic necrosis virus have altered virulence and tissue tropism.

Journal of virology - 1 Dec 1994

Kim C H, Winton J R, Leong J C

Abstract excerpt

Infectious hematopoietic necrosis virus (IHNV) is a rhabdovirus that causes an acute disease in salmon and trout. In this study, a correlation between changes in tissue tropism and specific changes in the virus genome appeared to be made by examining four IHNV neutralization-resistant variants (RB-1, RB-2, RB-3, and RB-4) that had been selected with the glycoprotein (G)-specific monoclonal antibody RB/B5. These...

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Identifiers

PMID: 7525991
DOI: 10.1128/JVI.68.12.8447-8453.1994
PMCID: PMC237321

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