Article
Neutralization-resistant variants of infectious hematopoietic necrosis virus have altered virulence and tissue tropism.
Journal of virology - 1 Dec 1994
Kim C H, Winton J R, Leong J C
Abstract excerpt
Infectious hematopoietic necrosis virus (IHNV) is a rhabdovirus that causes an acute disease in salmon and trout. In this study, a correlation between changes in tissue tropism and specific changes in the virus genome appeared to be made by examining four IHNV neutralization-resistant variants (R...
Topics
- Animals
- Antibodies, Monoclonal
- Antigens, Viral
- Brain
- Carcinoma
- Cell Line
- Epitopes
- Genes, Viral
- Genetic Variation
- Glycoproteins
- Herpesviridae Infections
- Liver
- Models, Structural
- Neutralization Tests
- Oncorhynchus mykiss
- Point Mutation
- Protein Structure, Secondary
- Rhabdoviridae