Article
Modulation of cell migration and vessel formation by vascular endothelial growth factor and basic fibroblast growth factor in cultured embryonic heart.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Aug 1995
Ratajska A, Torry R J, Kitten G T, Kolker S J, Tomanek R J
Abstract excerpt
Vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) stimulate endothelial cell proliferation, migration, and vascular tube formation. We tested the hypotheses that these growth factors stimulate (1) cell migration and (2) assembly into cord-like structures in embryonic rat heart explants cultured on collagen gels. Atrial and ventricular explants from rat embryos at 12 (E12,...
Topics
- Animals
- Blotting, Western
- Cell Differentiation
- Cell Movement
- Coronary Vessels
- Endothelial Growth Factors
- Female
- Fetal Heart
- Fibroblast Growth Factor 2
- Heart Atria