Fine mapping of MEP1A, the gene encoding the alpha subunit of the metalloendopeptidase meprin, to human chromosome 6P21.

doi:10.1006/bbrc.1995.2668

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Fine mapping of MEP1A, the gene encoding the alpha subunit of the metalloendopeptidase meprin, to human chromosome 6P21.

Biochemical and biophysical research communications - 13 Nov 1995

Jiang W, Dewald G, Brundage E, Mücher G, Schildhaus H U, Zerres K, Bond J S

Abstract excerpt

Meprins are kidney and intestinal proteases encoded by two distinct genes, MEP1A and MEP1B. MEP1A was previously mapped to human chromosome 6p, by the use of radiation and somatic cell hybrids, in the region containing the gene for autosomal recessive polycystic kidney disease (ARPKD). We now report the fine mapping of MEP1A using yeast artificial chromosome clones, and linkage analysis of ARPKD families. The...

Topics

Alleles
Animals
Base Sequence
Chromosome Mapping
Chromosomes, Artificial, Yeast
Chromosomes, Human, Pair 6
DNA Primers
DNA, Complementary
Female
Genes, Recessive
Genetic Linkage

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Hominidae

Humans

Hybrid Cells

Intestines

Kidney

Macromolecular Substances

Male

Source

Open in PubMed

Identifiers

PMID: 7488157
DOI: 10.1006/bbrc.1995.2668

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7488157-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fine mapping of MEP1A, the gene encoding the alpha subunit of the metalloendopeptidase meprin, to human chromosome 6P21.PMID 7488157Read ↗

Assignment of the human renal dipeptidase gene (DPEP1) to band q24 of chromosome 16Semantic proximity Read ↗

Physical and linkage mapping of the human and murine genes for the alpha 1 chain of type IX collagen (COL9A1).Semantic proximity Read ↗

Fine Physical Mapping of the Human Matrix Metalloproteinase Genes Clustered on Chromosome 11q22.3Semantic proximity Read ↗

A detailed physical map of the 6p reading disability locus, including new markers and confirmation of recombination suppression.Semantic proximity Read ↗

Fine mapping of the human SCIDX1 locus at Xq12-13.1.Semantic proximity Read ↗

Human Na+/H+ exchanger genes : identification of polymorphisms by radiation hybrid mapping and analysis of linkage in end-stage renal disease.Semantic proximity Read ↗

Uniparental disomy for chromosome 6 results in steroid 21-hydroxylase deficiency: evidence of different genetic mechanisms involved in the production of the disease.Semantic proximity Read ↗

High-resolution genetic and physical mapping of multiple epiphyseal dysplasia and pseudoachondroplasia mutations at chromosome 19p13.1-p12.Semantic proximity Read ↗

Exclusion of BMP6 as a candidate gene for cleidocranial dysplasia.Semantic proximity Read ↗

A HindIII RFLP at the FTHP1 locus on chromosome 6.Semantic proximity Read ↗

Chromosomal assignment of canine TSC2, PKD1 and CLN3 genes by radiation hybrid- and linkage analyses.Semantic proximity Read ↗

Integrated radiation hybrid map of human chromosome 2p13: possible involvement of dynactin in neuromuscular diseases.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.