UKEMS trial: bacterial mutation tests of 4-chloromethylbiphenyl, 4-hydroxymethylbiphenyl, and benzyl chloride, using E. coli WP2uvrA(pKM101) and S. typhimurium TA98 and TA100.

doi:10.1016/0165-1218(82)90018-0

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Article

UKEMS trial: bacterial mutation tests of 4-chloromethylbiphenyl, 4-hydroxymethylbiphenyl, and benzyl chloride, using E. coli WP2uvrA(pKM101) and S. typhimurium TA98 and TA100.

Mutation research - 1 Jan 2000

Venitt S, Crofton-Sleigh C, Bosworth D A

Abstract excerpt

4CMB, 4HMB and BC were assayed in plate tests, using E. coli WP2urvA(pKM101), and S. typhimurium TA98 and TA100, in the presence or absence of microsomal activation. 4CMB was also assayed in fluctuation tests using E. coli WP2uvrA(pKM101). 4HMB was uniformly negative, and 4CMB was mutagenic to al...

Topics

Benzyl Compounds
Biphenyl Compounds
Escherichia coli
Mutagenicity Tests
Mutagens
Mutation
Salmonella typhimurium
Species Specificity
Structure-Activity Relationship

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