Article
Switching of subunit composition of muscle spectrin during myogenesis in vitro.
Nature - 1 Jan 2000
Nelson W J, Lazarides E
Abstract excerpt
Spectrin comprises a family of polypeptides thought to be involved in mediating linkage of actin filaments to the plasma membrane in a wide variety of cell types (for reviews see refs 1-3). Spectrin is present as a tetramer composed of two non-identical subunits. Most cells express a common subunit with a molecular weight (Mr) of 240,000 (240 K; termed alpha-spectrin) in association with a polymorphic cell...
Topics
- Animals
- Chick Embryo
- Macromolecular Substances
- Membrane Proteins
- Muscle Development
- Phenotype
- Spectrin
- Tissue Distribution