Demonstration of acid alpha-glucosidase in different types of Pompe disease by use of an immunochemical method.

doi:10.1016/0022-510x(84)90001-7

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Article

Demonstration of acid alpha-glucosidase in different types of Pompe disease by use of an immunochemical method.

Journal of the neurological sciences - 1 Jan 2000

Ninomiya N, Matsuda I, Matsuoka T, Iwamasa T, Nonaka I

Abstract excerpt

The nature of mutant acid alpha-glucosidase (AAG) in muscle was studied in 6 patients with Pompe disease, consisting of 2 each of the infantile, childhood and adult types. Anti-human liver AAG rabbit antibody prepared in the present study was confirmed to be monospecific by immunodiffusion, immunotitration and immunohistochemical methods. It was found by the immunodiffusion and enzyme immunoassay methods using...

Topics

Adult
Biopsy
Child
Child, Preschool
Female
Glucosidases
Glycogen Storage Disease
Glycogen Storage Disease Type II
Humans
Hydrogen-Ion Concentration
Immunodiffusion

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Immunoenzyme Techniques

Infant

Liver

Male

Muscles

Mutation

alpha-Glucosidases

Source

Open in PubMed

Identifiers

PMID: 6442343
DOI: 10.1016/0022-510x(84)90001-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-6442343-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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