Article
Precision Medicine in Overlap Syndrome (COPD-Obstructive Sleep Apnea): From Phenotypes and Endotypes to Treatable Traits.
Advances in respiratory medicine - 1 Sept 2026
Afloarei Carina Adina, Zabara Antal Andreea, Toma David, Pintilie Adriana Loredana, Pitusac Georgiana, Tiron Raluca, Birladeanu Tudor, Zaharia Teodor, Crisan Dabija Radu
Abstract excerpt
INTRODUCTION: COPD-OSA overlap syndrome (OVS) is defined by the coexistence of chronic obstructive pulmonary disease and obstructive sleep apnea syndrome in the same patient; it affects 28.3% of patients evaluated for either condition and is associated with significantly higher mortality compared to either pathology in isolation. Current therapeutic approaches, involving PAP therapy and bronchodilation, treat...
Read the complete abstract on PubMedTopics
- Humans
- Precision Medicine
- Sleep Apnea, Obstructive
- Phenotype
- Pulmonary Disease, Chronic Obstructive