Suggestive causal associations between 17 autoimmune diseases and pancreatitis: A two-sample Mendelian randomization study.

doi:10.1097/MD.0000000000050766

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Article

Suggestive causal associations between 17 autoimmune diseases and pancreatitis: A two-sample Mendelian randomization study.

Medicine - 18 Sept 2026

Huang Dehua, Li Yun, Li Zhenyu, Chen Chongfa, Wang Huijuan, You Hanxiao, Zhang Jinfan, Dai Shangnan, Wang Guangfu, Lu Chunhui, Li Chenchen, Sun Feihu, Yin Lingdi, Miao Yi

Abstract excerpt

The relationship between different autoimmune diseases (ADs) and pancreatitis has been reported in epidemiological studies. This study systematically investigated the causal effects of ADs factors on pancreatitis using Mendelian randomization (MR). We selected 17 common ADs as exposures from the largest genome-wide association study dataset in Europe. The outcome variables included acute pancreatitis (AP),...

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Topics

Humans
Mendelian Randomization Analysis
Autoimmune Diseases
Pancreatitis
Diabetes Mellitus, Type 1

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Genome-Wide Association Study

Colitis, Ulcerative

Genetic Predisposition to Disease

Europe

Cholangitis, Sclerosing

Risk Factors

Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 42760723
DOI: 10.1097/MD.0000000000050766
PMCID: PMC13593168

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