Article
Diversity at the HYP1 locus in potato cyst nematodes does not result from developmentally-programmed somatic mutations.
PloS one - 1 Jan 2026
Hanlon Vincent C T, Sonawala Unnati, Raza Cian A A, Kalkert Luisa, Harpum George, Burkhardt Lukas A, Helder Johannes, Eves-van den Akker Sebastian
Abstract excerpt
Most genetic diversity stems from spontaneous mutations, that is, errors in DNA repair or replication. But for dozens of organisms across the tree of life, mutations at specific loci are not spontaneous but developmentally programmed: effectively, some organisms edit their own DNA sequences. This is perhaps most common among pathogens and parasites, many of which use editing to diversify genes that produce...
Read the complete abstract on PubMedTopics
- Animals
- Solanum tuberosum
- Mutation
- Genetic Variation
- Alleles
- Helminth Proteins
