Animal Models of Hyperoxaluria and Their Relevance for Fundamental Research and Clinical Practice.

Abstract excerpt

In vivo models have been central to understanding hyperoxaluria pathogenesis and to the development of emerging therapeutic strategies, but no single model fully reproduces the complexity of human disease. This narrative review critically evaluates currently available in vivo models of hyperoxaluria and provides a framework for their selection, interpretation, and integration according to the specific phenotype...

Topics

• Animals
• Humans
• Disease Models, Animal
• Hyperoxaluria
• Phenotype