Article
Genomic, virulent and phenotypic characterization of a cerebrospinal fluid-derived ST86-KL2 hypervirulent Klebsiella pneumoniae isolate from a patient with meningitis and diabetes mellitus.
BMC microbiology - 22 Jul 2026
Lai Xiyun, Zhu Xinyu, Yan Jie, Zou Tingjian, Chen Mengyuan, Chen Heng, Tang Xiaofang, Wang Qiang
Abstract excerpt
BACKGROUND: Hypervirulent Klebsiella pneumoniae (hvKP) is an important cause of invasive community-acquired infection, particularly in individuals with diabetes mellitus. However, cerebrospinal fluid (CSF)-derived hvKP isolates, especially those belonging to the ST86-KL2 lineage, remain poorly characterized at the integrated clinical, genomic, and phenotypic levels. METHODS: A K. pneumoniae isolate, designated...
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- Humans
- Klebsiella pneumoniae
- Phylogeny
- Klebsiella Infections
- Animals
- Virulence