Article
Genetic Variation and Evolutionary Characteristics of Coxsackievirus B1: F3 Subtype Associated With Hand, Foot and Mouth Disease in China.
Journal of medical virology - 1 Sept 2026
Lin Jie, Lin Xiaojuan, Yang Qian, Ji Tianjiao, Xiao Jinbo, Zhu Shuangli, Wang Dongyan, Li Xiaolei, Zhu Hui, Sun Qiang, Zhu Chenglin, Gao Shang, Xu Yabei, Zhang Yong, Yan Dongmei
Abstract excerpt
Coxsackievirus B1 (CV-B1) is primarily associated with meningitis but can also cause localized outbreaks of hand, foot, and mouth disease (HFMD). This study analyzed the genetic diversity of the VP1 gene in 39 strains of the CVB1 virus isolated from HFMD children across 15 provinces in China between 2010 and 2024, as well as 179 strains from 17 countries. Based on the average nucleotide difference of VP1 gene, we...
Read the complete abstract on PubMedTopics
- Humans
- Hand, Foot and Mouth Disease
- China
- Genetic Variation
- Enterovirus B, Human
