OsASA2 Loss-of-Function Confers Broad-Spectrum Disease Resistance and Triggers Cell Death by Regulating Anthranilate Synthase Activity in Rice.

doi:10.1111/mpp.70340

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OsASA2 Loss-of-Function Confers Broad-Spectrum Disease Resistance and Triggers Cell Death by Regulating Anthranilate Synthase Activity in Rice.

Molecular plant pathology - 1 Sept 2026

Guo Mingliang, Jiang Shuyu, Li Ying, Chen Zhiwei, Li Shengping, Chen Ziqiang, Niu Yuqing, Wang Mo, Chen Songbiao, Tian Dagang

Abstract excerpt

Lesion mimic mutants are valuable for studying plant cell death and defence mechanisms. Here, we identify a rice lesion mimic mutant, osasa2-1, which exhibits spontaneous cell death and enhanced disease resistance. The mutant displays white spots on leaves that develop into large brown lesions. Histological analysis reveals increased cell death and H2O2 accumulation. Map-based cloning identified the causal gene...

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Topics

Oryza
Anthranilate Synthase
Cell Death
Disease Resistance
Plant Diseases
Xanthomonas

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Plant Proteins

Magnaporthe

Gene Expression Regulation, Plant

Reactive Oxygen Species

Hydrogen Peroxide

Loss of Function Mutation

Mutation

Source

Open in PubMed Open full text

Identifiers

PMID: 42703047
DOI: 10.1111/mpp.70340
PMCID: PMC13547970

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