Article
Knockout of SfVipR2 confers Vip3Aa resistance in Spodoptera frugiperda with evidence of genetic complementation among non-allelic mutations of SfVipR1, SfVipR2, and SfCHS2.
Pesticide biochemistry and physiology - 1 Sept 2026
Pang Xinru, Zhang Zheng, Qin Duo, Bachler Andreas, Yang Yihua, Wu Yidong
Abstract excerpt
The Vip3Aa protein from Bacillus thuringiensis is widely deployed in transgenic crops to control lepidopteran pests, including the fall armyworm Spodoptera frugiperda, a highly invasive, polyphagous pest of global importance. Loss-of-function mutations in SfVipR1 (a thyroglobulin-like gene) and SfCHS2 (chitin synthase 2) have previously been confirmed to confer high-level, recessive resistance to Vip3Aa in S....
Read the complete abstract on PubMedTopics
- Animals
- Spodoptera
- Bacterial Proteins
- Gene Knockout Techniques
- Mutation
- Genetic Complementation Test
