Epidermolysis Bullosa Classification and Current Approach to Diagnosis.

Abstract excerpt

Epidermolysis bullosa (EB) is a heterogeneous group of rare genodermatoses marked by skin fragility and bullae formation induced by minor trauma. Pathologic variants in at least 21 genes are associated with EB, grouped into four major subtypes based predominantly on the plane of cleavage within the skin. EB simplex is characterized by epidermal bullae formation and is due to gene mutations that affect epidermal...

Topics

• Humans
• Epidermolysis Bullosa
• Mutation