Virulence and Invasion Profiles of Escherichia coli Across One Health Reservoirs: Genomic Insights into High-Risk Clones and Their Defense Systems.

doi:10.3390/pathogens15080812

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Virulence and Invasion Profiles of Escherichia coli Across One Health Reservoirs: Genomic Insights into High-Risk Clones and Their Defense Systems.

Pathogens (Basel, Switzerland) - 1 Aug 2026

Martínez-Álvarez Sandra, Herrera-Espejo Soraya, Zarazaga Myriam, Höfle Ursula, Pachón-Ibáñez María Eugenia, Torres Carmen

Abstract excerpt

Escherichia coli is a genetically diverse species encompassing both commensal and pathogenic lineages capable of transitioning among various hosts. Within a One Health framework, we conducted a targeted screening of 38 E. coli strains isolated from wildlife, livestock, and food reservoirs to characterize their pathogenic potential by integrating genomic and phenotypic approaches. In vitro functional assays,...

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PMID: 42654749
DOI: 10.3390/pathogens15080812
PMCID: PMC13516913

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