Article
Association of GPR30 Genetic Variants with Recurrent Implantation Failure: A Case-Control Study Comparing Fertile Women, ART Success and RIF Patients.
Reproductive sciences (Thousand Oaks, Calif.) - 1 Sept 2026
Khatibi Elham, Saeedi Fatemeh, Boroujeni Parnaz Borjian, Mashayekhi Mehri, Ghaheri Azadeh, Zamanian Mohammadreza
Abstract excerpt
GPR30 (G-protein coupled receptor 30) plays a key role in regulating reproductive processes, particularly through estrogen signaling. Previous studies have linked GPR30 polymorphisms to female reproductive disorders such as infertility, recurrent pregnancy loss, endometriosis, leiomyoma, and breast or ovarian cancers. This study investigated, for the first time, the association between two GPR30 polymorphisms...
Read the complete abstract on PubMedTopics
- Humans
- Female
- Receptors, G-Protein-Coupled
- Case-Control Studies
- Infertility, Female
- Adult
