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Article

Nuclear mitochondrial sequences in great ape Telomere-to-Telomere genomes

18 Aug 2026

Abstract excerpt

Mitochondrial sequences have integrated into the nuclear genome since the origin of eukaryotes. Recent insertions that retain homology to extant mitochondrial DNA (mtDNA), termed NUMTs, confound mtDNA sequence analysis. Here, we use great ape Telomere-to-Telomere (T2T) genomes to study NUMTs in bonobo, chimpanzee, human, gorilla, and Bornean and Sumatran orangutans. A phylogeny based on shared and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 42613155
DOI: 10.1101/gr.280875.125

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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