Article
Multisite evaluation of blAST, a direct-from-urine phenotypic antimicrobial susceptibility test, compared with reference broth microdilution.
Diagnostic microbiology and infectious disease - 1 Nov 2026
Lwande Joel S, Porter Alex, McQuaid Maeve, Waidely Eric, Tong Winnie, Huband Michael D, Rhomberg Paul R, Young Jesse, Vause Carrie V, Kittle Joseph D
Abstract excerpt
Traditional antimicrobial susceptibility testing (AST) is time-consuming and limited by the need to isolate bacteria. The Bio-Labeling Antibiotic Susceptibility Test (blAST) is a population-level direct-sample ∼6-h phenotypic AST that measures protein synthesis through incorporation of non-canonical amino acids and click chemistry detection. This multi-site study evaluated blAST against urinary tract infection...
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