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Article

Hidden deficiency under bright skies: Vitamin D prevalence and genetic associations in African Type 2 diabetes: A systematic review and meta-analysis.

PloS one - 1 Jan 2026

Abera Eyob Girma, Himbaro Samuel Alemu, Megersa Surafel Worku, Leta Tesfaye Adugna, Gebremichael Ermias Habte

Abstract excerpt

BACKGROUND: Type 2 diabetes mellitus (T2DM) has become a significant health challenge in Africa, with rapidly increasing prevalence. Despite abundant sunlight, vitamin D deficiency (VDD) is prevalent and may influence glucose metabolism and insulin resistance. Genetic factors, including vitamin D receptor (VDR) polymorphisms, may modify these effects. This systematic review and meta-analysis aimed to estimate the...

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Diabetes Mellitus, Type 2
VDR gene
Genetic Predisposition to Disease
Prevalence
Receptors, Calcitriol

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Vitamin D Deficiency

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PMID: 42497152
DOI: 10.1371/journal.pone.0354518
PMCID: PMC13399315

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VDR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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