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Article

Comprehensive Characterization of Clinical Phenotypes and CTG Repeat-Associated Manifestations in Spinocerebellar Ataxia Type 8.

Cerebellum (London, England) - 22 Jul 2026

Yang Deli, Tang Chao, Zhan Yu, Yang Lang, Lei Xiaoyang, Peng Xiaoxue, He Dian

Abstract excerpt

Spinocerebellar ataxia type 8 (SCA8) is traditionally characterized as a cerebellar syndrome, yet emerging evidence suggests significant phenotypic heterogeneity. The complex non-linear relationship between genetic burden and clinical severity remains understudied. We analyzed 172 SCA8 patients using advanced data mining techniques. Complete clinical demographic data were available for the cohort, with precise...

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PMID: 42484951
DOI: 10.1007/s12311-026-02053-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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