MATRIX: rapid quantification of total and active microbial cells with single-cell phenotypes for environmental microbiomes.

Abstract excerpt

Quantifying the abundance and activity of bacteria within populations and communities is fundamental to systems microbiology and microbiome research. Yet direct microscopic cell counting remains low throughput, labor-intensive, and prone to user variability, leading many researchers to rely on indirect proxies such as optical density or multicopy marker-gene quantification. These indirect approaches do not...

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