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High pathogenicity avian influenza A (H5N1) viruses isolated from poultry and wild birds in Japan during the 2024-2025 season.

Microbiology spectrum - 4 Aug 2026

Takadate Yoshihiro, Nishiura Hayate, Kumagai Asuka, Mine Junki, Tsunekuni Ryota, Sakuma Saki, Soda Kosuke, Esaki Mana, Okuya Kosuke, Nabeshima Kei, Hiono Takahiro, Takakuwa Hiroki, Usui Tatsufumi, Ozawa Makoto, Onuma Manabu, Isoda Norikazu, Sakoda Yoshihiro, Uchida Yuko, Miyazawa Kohtaro

Abstract excerpt

H5N1 high pathogenicity avian influenza (HPAI) viruses of clade 2.3.4.4b continue to spread globally among wild birds and poultry, and diversify through gene reassortment. Since 2024, spillovers of H5N1 viruses have been reported in dairy cattle in the United States. Given the numerous HPAI outbreaks in poultry and wild birds in Japan during the 2024-2025 season, we aimed to examine the genetic diversity,...

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PMID: 42446198
DOI: 10.1128/spectrum.00293-26
PMCID: PMC13435830

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