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Congener-Specific Associations of Per- and Polyfluoroalkyl Substances With Obesity-Metabolic Phenotypes: A Multimodel Analysis.

Obesity (Silver Spring, Md.) - 1 Aug 2026

Sun Liyun, Zhang Mi, Gao Bingrui, Wang Mingyue, Guan Zhiyi, Kang Ziwei, Shan Zhongyan, Teng Weiping, Li Jing

Abstract excerpt

OBJECTIVE: This study aimed to investigate the associations between per- and polyfluoroalkyl substances (PFAS) and distinct obesity-metabolic phenotypes and explore underlying mechanisms. METHODS: A total of 8692 adults from NHANES 2003-2018 were classified into four phenotypes as follows: metabolically healthy obesity (MHO), metabolically unhealthy obesity (MUO), metabolically healthy non-obesity (MHNO), and...

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Identifiers

PMID: 42431848
DOI: 10.1002/oby.70259
PMCID: PMC13422252

Genes

PFAS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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