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Article

Predicting T790M mutation status in non-small cell lung cancer based on radiomics: A systematic review and meta-analysis.

PloS one - 1 Jan 2026

Chen Hongyang, Fan Bingjie, Yuan Mengqi, Wang Dandan, Qiao Chenxi, Qiu Na, Quan Xiaomin, Hou Wei

Abstract excerpt

BACKGROUND: Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) have revolutionized the prognosis for patients with EGFR-mutant lung cancer. The emergence of the T790M resistance mutation compromises the efficacy of EGFR-TKI therapy. Therefore, assessing EGFR T790M mutation status during non-small cell lung cancer (NSCLC) treatment is crucial for improving NSCLC prognosis. METHOD: PubMed,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42418457
DOI: 10.1371/journal.pone.0353257
PMCID: PMC13345267

Genes

EGFR
ITK

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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