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Development and externally validate MRI-based nomogram to assess EGFR and T790M mutations in patients with metastatic lung adenocarcinoma.

European radiology - 1 Oct 2022

Fan Ying, Dong Yue, Wang Huan, Wang Hongbo, Sun Xinyan, Wang Xiaoyu, Zhao Peng, Luo Yahong, Jiang Xiran

Abstract excerpt

OBJECTIVES: This study aims to explore values of multi-parametric MRI-based radiomics for detecting the epidermal growth factor receptor (EGFR) mutation and resistance (T790M) mutation in lung adenocarcinoma (LA) patients with spinal metastasis. METHODS: This study enrolled a group of 160 LA patients from our hospital (between Jan. 2017 and Feb. 2021) to build a primary cohort. An external cohort was developed...

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PMID: 35729427
DOI: 10.1007/s00330-022-08955-5

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