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Frailty phenotype transitions and functional improvements during a supervised exercise trial in older people with HIV: results from the HEALTH Trial.

Age and ageing - 2 Jul 2026

Oliveira Vitor H F, Dos Santos Andre P, Kulik Grace L, Horvat Davey Christine, Iriarte Evelyn, Jones Raymond, Wilson Melissa P, Khuu Vincent, Ghosh Debashis, Mawhinney Samantha, Jankowski Catherine M, Cook Paul, Erlandson Kristine M, Webel Allison R

Abstract excerpt

BACKGROUND: Frailty and sarcopenia contribute to functional decline in older people with HIV (PWH), yet intervention data remain limited. We evaluated changes in frailty phenotype status, sarcopenia-related outcomes and functional performance during a supervised exercise trial and assessed associations between baseline frailty, study withdrawal and intervention response. METHODS: The High-Intensity Exercise to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42407092
DOI: 10.1093/ageing/afag199
PMCID: PMC13402076

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