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Article

Rare variants in genes related to inborn errors of immunity in patients with rheumatoid arthritis and secondary immunodeficiency.

RMD open - 3 Jul 2026

Atschekzei Faranaz, Dubrowinskaja Natalia, Anim Manfred, Steinemann Doris, von Hardenberg Sandra, Hofmann Winfried, Geffers Robert, Witte Torsten, Sogkas Georgios

Abstract excerpt

OBJECTIVES: Treatment of rheumatoid arthritis (RA) relies on immunomodulatory drugs that can compromise immunity, inducing secondary immunodeficiency (SID). However, features of SID, such as hypogammaglobulinaemia and severe/recurrent infections, occur in only a minority of patients, suggesting a potential underlying genetic predisposition. Given the expanding spectrum of genes implicated in inborn errors of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42399081
DOI: 10.1136/rmdopen-2026-007046
PMCID: PMC13343069

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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