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Cloning-based analysis of MHC class II DRB variation and Enterocytozoon bieneusi association in the Amur tiger (Panthera tigris altaica).

Molecular and biochemical parasitology - 1 Sept 2026

Liu Yang, Xu Haitao, Zhang Yu, Zhao Yilin, Lv Zhiyou, Liu Mengqiu, Zhou Mengchao, Lu Yaxian, Yu Hongyan, Tian Hang, Zhou Shaochun, Tian Lihong, Hou Zhijun

Abstract excerpt

The polymorphism of major histocompatibility complex (MHC) class II classical genes is closely related to pathogen resistance, among which the second exon of the DRB gene has the highest variability. In this study, we analyzed exon 2 of the MHC class II DRB gene in 32 captive Amur tigers (Panthera tigris altaica) using a cloning-based sequencing approach to assess genetic diversity and its association with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 42336108
DOI: 10.1016/j.molbiopara.2026.111762

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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