Abdominal fat distribution phenotypes and metabolic risk in premenopausal Asian women: insights beyond general adiposity measures.

doi:10.1038/s41598-026-55520-x

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Article

Abdominal fat distribution phenotypes and metabolic risk in premenopausal Asian women: insights beyond general adiposity measures.

Scientific reports - 18 Jun 2026

Kway Yeshe M, Michael Navin, Kothandaraman Narasimhan, Yaligar Jadegoud, Tint Mya Thway, Tan Kok Hian, Godfrey Keith M, Gluckman Peter D, Chong Yap Seng, Leow Melvin Khee-Shing, Chan Jerry K Y, Chan Shiao-Yng, Fortier Marielle V, Eriksson Johan G, Huang Jonathan, Lee Yung Seng, Feng Mengling, Velan S Sendhil, Sadananthan Suresh Anand

Abstract excerpt

The rising prevalence of metabolic syndrome (MetS) and gestational diabetes mellitus (GDM) in women of reproductive age highlights their growing susceptibility to future cardiometabolic diseases. Both conditions signal early metabolic dysfunction tied to abdominal adiposity. We investigated whether relative abdominal adipose tissue (AAT) distribution characterises metabolic risk beyond general adiposity. Using...

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Topics

Adult
Female
Humans
Pregnancy
Abdominal Fat

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Adiposity

Asian People

Body Mass Index

Diabetes, Gestational

Magnetic Resonance Imaging

Metabolic Syndrome

Phenotype

Premenopause

Risk Factors

Singapore

Source

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Identifiers

PMID: 42315653
DOI: 10.1038/s41598-026-55520-x
PMCID: PMC13547274

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