Impact of the FTO rs9939609 risk allele on subcutaneous adipose tissue fatty acid composition in adults with obesity class 2 and 3.

doi:10.1371/journal.pone.0351698

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Article

Impact of the FTO rs9939609 risk allele on subcutaneous adipose tissue fatty acid composition in adults with obesity class 2 and 3.

PloS one - 1 Jan 2026

Mostad Ingrid Løvold, Grill Valdemar, Skarra Sissel, de Soysa Ann Kristin Hjelle, Fielding Barbara

Abstract excerpt

The FTO rs9939609 risk allele is linked to risk of obesity. Whether causality involves fatty acid (FA) metabolism remains to be fully investigated in adults with obesity. We tested for associations of the risk allele with the FA composition of android and gynoid subcutaneous adipose tissue. We recruited 95 participants with obesity class 2 and 3 and without diabetes, median BMI 42.8 (25th, 75th percentiles: 39.5,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 42308226
DOI: 10.1371/journal.pone.0351698
PMCID: PMC13274855

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