Bronchiolar adenoma and glandular papilloma/mixed squamous cell and glandular papilloma represent a continuous disease spectrum: revelations from combined histological and genetic analysis.

Abstract excerpt

AIMS: Despite their common bronchial/bronchiolar origin, the relationship between glandular/mixed papillomas (GPs/MPs) and bronchiolar adenomas (BAs) remains uncertain; therefore, this study aimed to elucidate it. METHODS AND RESULTS: We performed a combined clinicopathological and next-generation sequencing analysis of 6 GP/MP and 14 BA cases. The cases were classified into three groups based on...

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• Adenoma
• Aged
• Aged, 80 and over
• AKT1 gene
• Lung Neoplasms