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Whole-genome analysis of a novel Pandoraea sputorum lineage causing high-mortality bloodstream infections.

Microbial genomics - 1 Jun 2026

Wu Hua, Liu Lin, Li Shijia, Zhang Pei, Xing Ziling, Huang Qian, Kuang Dai, Liu Wei, Chen Chong, Xia Qianfeng

Abstract excerpt

Background. Pandoraea sputorum is an emerging multidrug-resistant pathogen primarily associated with cystic fibrosis. Bloodstream infections (BSIs) are rare but linked to high mortality. The genomic characteristics and evolutionary history of P. sputorum lineages causing BSIs remain poorly understood.Methods. We performed whole-genome sequencing on 18 P. sputorum isolates recovered from patients with BSIs in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42228388
DOI: 10.1099/mgen.0.001663
PMCID: PMC13229510

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